SOP SUBARASHI
Cell Regeneration,
Better Blood Circulation,
Anti-Hypertensive,
Organ Repair &
Anti-Blood Clot
Japan’s first triple peptide product, combining Hokkaido Oncorhynchus Keta Salmon Marine Placenta Peptide, Sardine
Peptide and FruitFlow Tomato Peptide. Combined with the synergy of 7 other active ingredients, SOP Surabashi activates your body own stem cells…
What is SOP Subarashi?
Japan's Ministry of Health, Labour and Welfare uses a regulatory term called
"Foods for Specified Health Uses" (FOSHU). These are not ordinary supplements;
they carry government-reviewed claims for physiological benefit.
The AFC corporation (Asayama Family Club) used that framework to develop
a powdered sachet they named SOP Surabashi.
The heart of the product is a triple-peptide matrix extracted from seafood and plants,
surrounded by a support team of seven bio-active compounds.
Its manufacturing process is so unusual that the company holds four cardiovascular patents.
Four Cardiovascular Patents
Cell Regeneration : JP 39462 3B
What Is It?
A Japanese-patented bioactive formulation
that activates the body’s own stem cells
to trigger natural cell regeneration.
This is the foundation of the Subarashi Triple Peptide system, combining marine-derived peptides for systemic rejuvenation
What Does It Do?
Stimulates Dormant Stem Cells: Reactivates stem cells that have become inactive due to aging or stress.
Promotes Tissue Renewal: Supports the regeneration of skin, muscle, organ, and immune cells—essential for healing and vitality.
Enables Self-Healing: Helps the body repair damaged tissues naturally, without synthetic drugs or invasive procedures.
Why It Matters
This patent represents a breakthrough in regenerative nutrition—offering a food-erivedd, clinically supported way to enhance cellular renewal and longevity from within.
Blood Flow: JP 3946239
What Is It?
A Japanese-patented bioactive formulation that enhances both microcirculation (tiny capillaries) and macrocirculation (larger blood vessels). It’s part of the Subarashi Triple Peptide system, known for its regenerative and cardiovascular support.
What Does It Do?
Improves Peripheral Blood Flow: Helps restore circulation in areas prone to poor blood supply—like extremities and skin.
Supports Vascular Health: Enhances elasticity and function of blood vessels, promoting smoother, more efficient blood flow.
Reduces Circulatory Stress: May help alleviate symptoms linked to sluggish circulation, such as cold hands/feet, fatigue, and poor wound healing
Why It Matters
This peptide-based solution offers a natural,
food-derived strategy to support cardiovascular health—ideal for aging populations, sedentary lifestyles, and metabolic syndrome.
Blood Pressure: JPWO-2003055901A1
What Is It?
A patented peptide formulation derived from enzymatically treated fish meat, known as Peptide SY. It’s fractionated using ethanol and water to isolate a blend rich in Val-Tyr, a dipeptide with potent blood pressure-lowering effects
What Does It Do?
Lowers Systolic & Diastolic Pressure: Peptide SY has been shown to reduce both systolic and diastolic blood pressure, making it effective for managing hypertension.
Mild Taste, High Safety: Unlike many bioactive peptides, it’s low in bitterness and safe for long-term use, making it ideal for functional foods or supplements.
Clinically Supported: Validated in randomized, double-blind, placebo-controlled trials for its efficacy in lowering blood pressure
Why It Matters
Peptide SY offers a natural, food-derived alternative to pharmaceutical antihypertensives—ideal for prehypertensive individuals or those seeking gentle, daily support for cardiovascular health.
Anti-Thrombotic: JP 2009538895A
What Is It?
A patented tomato-derived extract developed to reduce blood clot formation. It’s one of the few natural compounds shown to inhibit both platelet aggregation and fibrin formation, key drivers of thrombosis.
What Does It Do?
Inhibits Platelet Clumping: Prevents platelets from sticking together, reducing the risk of clot formation in veins and arteries.
Blocks Fibrin Mesh Formation: Disrupts the final step in clot development, helping maintain smoother blood flow.
Clinically Recognized: Designed to support vascular health without the bleeding risks associated with pharmaceutical anticoagulants
Why It Matters
This extract offers a gentle, food-based strategy for reducing thrombotic risk—ideal for people with sedentary lifestyles,
metabolic syndrome, or elevated clotting markers.
The Triple-Peptide Core: Nature's Molecular Toolbox
Salmon Ovary Peptides (SOP)
They’re bioactive compounds extracted from wild Hokkaido salmon eggs (roe) using a gentle, low-temperature enzymatic process. This preserves their potency and structure.
What Do They Do?
Boost Blood Vessel Health: They stimulate key growth factors—VEGF and FGF-2—that help repair and grow blood vessels.
Enhance Nitric Oxide Production: They increase nitric oxide synthase activity by 22%, which helps relax blood vessels and improve circulation.
Lower Blood Pressure: In a small human study, participants saw an average drop of 12 mmHg in systolic blood pressure after 8 weeks of use.
Why It Matters
This peptide blend shows promise for supporting cardiovascular health naturally—especially by improving endothelial function and reducing hypertension risk.
Sardine Peptides
They’re bioactive fragments derived from Pacific sardine proteins, broken down using a natural enzyme from Bacillus subtilis. This process unlocks their therapeutic potential.
What Do They Do?
Block Blood Pressure Enzymes: They strongly inhibit ACE (angiotensin-converting enzyme), which helps lower blood pressure. The inhibition is potent—just 9 µg/mL needed to cut activity in half.
Reduce Oxidative LDL: They lower oxidized LDL cholesterol by 18%, which helps protect arteries from damage.
Lower Blood Pressure: In animal studies, hypertensive rats experienced a 23 mmHg drop in systolic blood pressure within 4 weeks.
? Why It Matters
These peptides offer a natural, food-based strategy for managing hypertension and oxidative stress—two major drivers of cardiovascular disease.
Fruitflow® Vegan Peptides
It’s a water-soluble extract from ripe tomatoes, carefully processed to preserve its natural bioactive compounds. It’s the first-ever natural product to receive an EFSA-approved health claim for platelet function.
What Does It Do?
Reduces Platelet Stickiness: It inhibits platelet binding by about 25%, helping blood flow more freely.
Prevents Clumping: Within just 3 hours, it reduces platelet aggregation by 17%, lowering the risk of unwanted clot formation.
Clinically Recognized: Approved by the European Food Safety Authority for supporting healthy blood flow—without the bleeding risks of pharmaceutical antiplatelets.
Why It Matters
Fruitflow offers a gentle, food-based approach to cardiovascular protection—ideal for people with elevated clotting risk, metabolic syndrome, or lifestyle-related inflammation.
The Magnificent Seven: Supporting Ingredients
Binds LDL and reduces intimal accumulation. Down-regulates NF-κB, damping inflammation inside arterial walls.
Extracted from bonito skin; supplies desmosine cross-links. Mouse model showed 14% increase in aortic elasticity.
L-Glutathione
Master antioxidant that recycles vitamins C and E. Low plasma levels correlate with 30% higher CVD risk.
Type I & III provides proline & hydroxyproline. 12-week trial showed 6% LDL decrease and 14% CRP reduction.
Essential Amino Acids
Complete complex assists hepatic synthesis of albumin, maintaining oncotic pressure and fatty acid transport.
Nucleic Acids
RNA/DNA fragments stimulate macrophage phagocytosis, enhancing removal of oxidized LDL
through TLR-8 pathways.
Hyaluronic Acid
Hydrates and plumps the
skin for a radiant glow
How Do These Pieces Work Together?
Vascular Regeneration
SOP + elastin + collagen supply structural amino acids while up-regulating growth factors. Result: smoother, more elastic arterial walls.
Pressure Control
Sardine peptides inhibit ACE; glutathione improves NO availability; hyaluronic acid reduces s hear stress—jointly leading to lower blood pressure.
Anti-Thrombotic Action
Fruitflow decreases platelet stickiness; chondroitin modulates fibrin architecture; nucleic acids activate macrophage cleanup of plaque debris.
Imagine three concentric shields around your heart: inner lining repair, blood flow optimization, and clot prevention. Surabashi is designed to activate all three.
SOP Surabashi Gold: (Launched August 2025)
The Gold Standard in
Cell Regeneration &
Anti-Aging
Four New Patents and Three New Peptides
Four New Patents
Cell Rejuvenation
JP 5641734 B2: A patented Japanese process that extracts and stabilizes ultra-low-molecular-weight nucleopeptides—less than 500 Daltons—from salmon caviar. These tiny bioactive molecules are designed to penetrate deeply and activate key longevity pathways.
What Does It Do?
Activates SIRT1: Boosts cellular repair and mitochondrial health by stimulating this NAD-dependent enzyme.
Triggers AMPK: Enhances energy metabolism and stress resistance, mimicking the effects of fasting or exercise.
Stimulates FOXO3a: Promotes antioxidant defense, DNA repair, and cellular longevity.
Why It Matters
This peptide complex taps into the body’s natural anti-aging circuitry, offering a food-derived way to support cellular renewal, metabolic balance, and resilience against oxidative stress.
Anti-Aging Effect
JP 3899116: A patented peptide blend rich in anserine—a natural dipeptide made of histidine and β-alanine—comprising at least 60% anserine. This composition is designed to target cellular aging at its root.
What Does It Do?
Reduces Senescence Markers: It lowers levels of p16^INK4a and SA-β-gal, two key indicators of cellular aging and dysfunction.
Supports Youthful Cell Function: By modulating these markers, it helps maintain healthier, more resilient cells.
Bioavailable & Safe: Anserine is naturally found in muscle tissue and is well-tolerated, making it ideal for long-term use.
Why It Matters
This peptide composition offers a food-derived strategy to slow cellular aging—potentially improving skin health, muscle function, and metabolic resilience without synthetic interventions.
Liver Protection
JP 4247444 B2: What Is THD-12?
It’s a 12-amino-acid peptide cluster extracted from tuna heart tissue, developed under a Japanese patent. This bioactive sequence is designed to protect liver cells from chemical damage.
What Does It Do?
Lowers Liver Enzymes: THD-12 helps suppress the rise of ALT and AST, two key markers of liver stress and inflammation.
Protects Against Toxins: It’s especially effective after chemical exposure, reducing liver damage and promoting recovery.
Natural & Targeted: Derived from marine protein, it offers a food-based approach to liver support without synthetic additives.
Why It Matters
THD-12 represents a precision peptide therapy for liver health—ideal for those exposed to environmental toxins, medications, or metabolic stress.
Uric Acid Control
CN 108559764 B: What Is It?
A patented marine tripeptide fingerprint—a specific sequence of three amino acids—designed to act as a competitive inhibitor of xanthine oxidase, the enzyme responsible for producing uric acid.
What Does It Do?
Blocks Uric Acid Production: It competes with natural substrates to inhibit xanthine oxidase, with a strong binding affinity (Ki = 1.8 µM), helping reduce uric acid levels.
Targets Gout & Oxidative Stress: By lowering uric acid, it may help manage gout, metabolic syndrome, and oxidative damage linked to purine metabolism.
Marine-Derived & Bioactive: Extracted from marine organisms, it offers a food-based alternative to synthetic drugs like allopurinol.
Why It Matters
This tripeptide fingerprint represents a next-gen nutraceutical for managing hyperuricemia and inflammation—ideal for functional foods or supplements targeting joint health and metabolic balance.
The Three New Peptides:
Advanced Bioactive Components
Salmon Caviar Peptide (SCP)
What Is SCP-3?
It’s a nucleophosphopeptide—a tiny bioactive molecule (just 428 Daltons)—extracted from mature Oncorhynchus keta (chum salmon) roe using a cold enzymatic process that preserves its delicate structure and potency.
What Does It Do?
Activates Sirtuin-1: Triggers cellular longevity and repair pathways, mimicking fasting or NAD+ boosters. Boosts eNOS Phosphorylation: Enhances nitric oxide signaling, improving blood flow and vascular health. Stimulates Dermal Fibroblasts: Promotes skin regeneration by encouraging fibroblast proliferation—key for collagen production and wound healing.
Why It Matters
SCP-3 offers a precision peptide approach to skin rejuvenation and vascular support—ideal for anti-aging, recovery, and dermal repair protocols.
Salmon Anserine Peptide (SAP)
What Is It?
A bioactive extract from the skeletal muscle of spawning chum salmon, rich in anserine—a natural dipeptide made of histidine and β-alanine. This extract contains ≥ 60% anserine, making it highly potent.
What Does It Do?
Neutralizes Toxic Byproducts: Anserine scavenges reactive carbonyl species, which are harmful compounds linked to aging and chronic inflammation.
Suppresses Inflammaging: It helps reduce low-grade, chronic inflammation associated with aging—supporting healthier immune and metabolic function.
Boosts Brain Speed: Clinical trials show a 9% improvement in cognitive processing speed, especially in verbal episodic memory.
? Why It Matters
This marine-derived peptide offers a natural strategy for brain and body rejuvenation—ideal for aging populations, cognitive support, and anti-inflammatory protocols.
Tuna Heart Peptide (THP)
What Is THD-12?
THD-12 is a 12-amino-acid peptide extracted from the cardiac tissue of Thunnus obesus (bigeye tuna). This marine-derived sequence is engineered for targeted liver protection and metabolic enhancement.
What Does It Do?
Protects Liver Cells: THD-12 reduces the elevation of liver enzymes ALT and AST by 48%, signaling reduced liver stress after chemical exposure. Activates PPAR-α: This nuclear receptor boosts fatty acid metabolism, helping the liver process lipids more efficiently.
Supports Detox & Recovery: Ideal for individuals exposed to toxins, medications, or metabolic overload.
Why It Matters
THD-12 offers a precision peptide solution for liver health—combining detox support, metabolic regulation, and cellular protection in one marine-sourced molecule.
Mechanistic Synergy:
Comprehensive Protection Network
Triple Peptide Core
Salmon Ovary + Sardine + Fruitflow enhance endothelial function and lower platelet
reactivity
New Peptide Triad
SCP + SAP + THP address cellular aging, neuroprotection, hepatoprotection, and uric-acid control
Cofactor Matrix
Chondroitin and companions support extracellular matrix resilience and antioxidant buffering
Imagine three concentric shields around your heart: inner lining repair, blood flow optimization, and clot prevention. Surabashi is designed to activate all three.
SOP SUBARASHI VIDEO
BENEFITS OF SURABASHI
Regenerate from Within with SOP SUBARASHI
SOP SUBARASHI is a scientifically formulated stem cell activator that supports natural cellular regeneration. By nourishing both active and dormant stem cells, it helps the body replace damaged or aging cells with new, functional ones—enhancing tissue repair, vitality, and overall wellness.
This advanced peptide-based supplement promotes self-healing by activating key regenerative pathways, making it a powerful ally in anti-aging, immune support, and metabolic recovery. Regular use of SOP SUBARASHI offers a safe, food-derived therapy for those seeking to optimize health at the cellular level.
Cellular Regeneration &
Rejuvenation
✔ Repairs damaged cells and regenerates aging tissues
✔ Reactivates dormant cells to optimize body function
✔ Helps combat fatigue and supports overall vitality
✔ Aids in post-operative healing and overall recovery
Cardiovascular & Circulatory Health
✔ Supports healthy blood pressure levels
✔ Promotes heart health and function
✔ Aids in preventing blood clots and vascular issues
✔ Helps manage cholesterol levels
✔ Supports stroke recovery and prevention
Kidney & Metabolic Health
✔ Supports kidney function and helps prevent albumin release in
kidney failure patients
✔ Aids in pancreatic health and glucose tolerance, beneficial for
diabetes management
✔ Helps regulate hormonal balance
✔ Promotes better metabolism and energy levels
Liver Support
✔ targets liver protection and metabolic enhancement.
✔ reduces the elevation of liver enzymes
✔ boosts fatty acid metabolism, helping the liver process lipids more efficiently.
Musculoskeletal Health
✔ Helps relieve chronic pain
✔ Supports healthy joint lubrication, improving mobility
✔ Reduces the risk of inflammation and joint discomfort
✔ Strengthens bones and supports skeletal health
✔ Helps prevent osteoporosis and age-related bone density loss
Skin Health & Anti-Aging
✔ Helps reduce wrinkles and promotes youthful skin
✔ Aids in hair growth and scalp health
Uric Acid Reduction
✔ By lowering uric acid, SOP Surabashi may help manage gout, metabolic syndrome, and oxidative damage linked to purine
metabolism.
How To Consume SOP SUBARASHI
Dosing:
Commercial product comes in 3.5g sachet. Morning intake recommended as Fruitflow's platelet effect peaks 3 hours post-ingestion.
Safety & Contraindications
No CYP450 inhibition at therapeutic doses. Theoretical synergy with ACE inhibitorsor antiplatelets means monitor blood pressure and platelet function if
combining therapies.
Drug Interactions
Look for GMP and ISO-22000 certification. Counterfeits exist online; verify batch number on AFC's website. Ensure authentic sourcing for safety.
Safety & Contraindications
Avoid if shellfish/fish allergy. Monitor INR if on warfarin. No studies in
pregnancy/lactation. Adverse events limited to mild fishy after-taste (2%) and transient nausea (1%).
Disclaimer: The health products and information we provide are for general reference only and not medical advice, diagnosis, or treatment. Individual results may vary, so please make informed choices based on your health condition. Consult a medical professional if you have any health concerns before using our products. Our company is not liable for any related issues. By purchasing our products, you agree to this disclaimer.
AFC Global Super Foods
Empowering healing through premium grade, patented ingredients and scientifically proven peptide supplements.
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